How chloroform anesthesia reached Lowell, Massachusetts: From Simpson's pamphlet to Gladwin's advertisement.

J.Y. Simpson of Edinburgh, Scotland discovered chloroform anesthesia in November 1847. During this time, W.T.G. Morton's agents had been collecting royalties for the use of ether across much of the United States. After reading about the advantages of chloroform as cited in C.T. Jackson's writings in the Boston Daily Atlas, S.F. Gladwin, a dentist in Lowell, Massachusetts, who had been reluctant to pay any ether royalties, demonstrated his independence and opportunism in swiftly adopting chloroform in his practice and publicizing its use through local advertisements.

Racial degeneration, mental hygiene, and the beginning of Peruvian psychiatry, 1922-1934.

Between 1922 and 1934, three pamphlets and a series of articles on mental hygiene were published in important newspapers in Lima, Peru. Their authors were Hermilio Valdizán and Honorio Delgado, two members of the first generation of psychiatrists in the country. These mass publications aimed to educate the population on what mental illness was, as well as its causes and symptoms. In addition, they sought to promote the figure of the psychiatrist as a specialist in "madness" whose recommendations should be heeded in family life. To that end, these publications contained true cases, related in melodramatic language, in order to reach a broader audience. Beyond their educative intention, these publications used ideas that Peruvian elites held about racial differentiation, because they were aimed at White and mestizo readers and had the express intention of preventing racial "degeneration." The analysis of this primary source material is complemented with other texts by Valdizán that sought to comprehend the manifestations of insanity among Native Peruvians, for which he used degeneration theory to explain the degree of "backwardness" observed among the races that were considered inferior. This article seeks to analyze the viewpoints held on racial differences by the most significant members of Peru's first generation of psychiatrists, in which degeneration theory was key in explaining the differences between human groups and in justifying the superiority of Whites and Western culture in the Peruvian state's mestizo identity initiative. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

[José Ignacio Bartolache y Díaz de Posada: his contributions to medicine]. / José Ignacio Bartolache y Díaz de Posada: sus aportes a la medicina.

During 18th century in New Spain, the strong link between religion and science hindered scientific growth. Conservatism and scholasticism pervaded educational institutions. Within this restricted context, a scientific community conformed mainly by creoles fulfilled their desire and need to know more as they had access to European books, which allowed erudite leading figures, such as Dr. José Ignacio Bartolache y Díaz de Posada, propel innovative ideas in medicine and pharmacy. Dr. Bartolache was considered sacrilegious and scandalous by the ecclesiastical authorities of that epoch. He favored the performance of human body dissections to improve medical education, as well as the anatomical proposals of Vesalius against Galeno's classical anatomy. He contributed to the dissemination of knowledge as he created the first medical magazine in the American continent: El Mercurio Volante (The Flying Mercury); he also printed medical pamphlets and flyers, some of which were published in Nahuatl and Spanish, as the prescriptions for martial pills, reformulated by himself. Physician ahead of his time, he was characterized by his professional humanism and the comprehensive treatment of patients; he emphasized the rational use of medications, without distinction of social class. His sensitivity allowed him to bring medical knowledge and treatment of illnesses closer to the most vulnerable. Another of his contributions, ahead of his time, was the recognition he gave women for the intelligence and ability they showed, equal to men, when accessing education.

En el siglo XVIII en la Nueva España, el fuerte vínculo entre la religión y la ciencia obstaculizaba el crecimiento científico. El conservadurismo y la escolástica permeaban las instituciones educativas. En este restringido contexto, una comunidad científica conformada en su mayoría por criollos se mantuvo inquieta y ante su necesidad de saber más, obtuvo acceso a libros europeos que permitieron a figuras ilustradas, como el doctor José Ignacio Bartolache y Díaz de Posada, impulsar ideas innovadoras en la medicina y la farmacia. El doctor Bartolache fue considerado sacrílego y escandaloso por las autoridades eclesiásticas de la época. Fue partidario de que se realizaran disecciones al cuerpo humano para mejorar la enseñanza de la medicina, así como de los planteamientos anatómicos de Vesalio frente a la anatomía clásica de Galeno. Impulsó la divulgación del conocimiento con la creación de la primera revista médica del continente americano, El Mercurio Volante, y también imprimió panfletos y folletos médicos, algunos publicados en náhuatl y español, como la prescripción de las pastillas marciales reformuladas por él. Médico innovador de la época, se caracterizó por su humanismo profesional y el tratamiento integral del paciente; hacía énfasis en el uso racional de los medicamentos, sin distinción de clases sociales. Su sensibilidad le permitió acercar el conocimiento médico y el tratamiento de los males a los más desprotegidos. Otra de sus aportaciones, adelantadas a su tiempo, fue el reconocimiento que otorgó a las mujeres por la inteligencia y capacidad que mostraron, al igual a los hombres, al acceder a la educación.

Representing AIDS in Comics.

Matthew P. McAllister wrote: "Comic books can and have contributed positively to the discourse about AIDS: images that encourage true education, understanding and compassion can help cope with a biomedical condition which has more than a biomedical relevance" [1]. With this in mind, I combined a 23-narrator oral history and my personal memoir about an inpatient Chicago AIDS hospital unit in my book, Taking Turns: Stories from HIV/AIDS Care Unit 371. In doing so, I built upon the existing rich history of HIV/AIDS in comics, which this article will briefly describe. Although not a comprehensive review of the intersection of AIDS and comics, the book is a tour through influences that proved useful to me. In addition, in making my book, I faced a distinct ethical issue with regard to representing patient experiences with HIV/AIDS, and I describe here how I addressed it.

[Ophthalmological reading tests : Part 1: historical aspects]. / Ophthalmologische Leseproben : Teil 1: Historische Aspekte.

BACKGROUND: The objective of this article was an analytical review of reading charts with regard to the historical background, printing techniques, print quality and print size. METHODS: For this study original historical reading charts (Jaeger, Snellen, Nieden and Birkhäuser) were investigated microscopically by measuring the lower case letter sizes (iNexis VMA 2520, Nikon, Tokyo). Calculations were made according to EN ISO 8596 and the recommendations of the International Research Council. RESULTS: In the mid-nineteenth century various reading cards were published; however, at that time it was not possible to print lower case letters according to exactly defined standards. Thus, these reading cards were not comparable to each other or between different language versions. At a reading distance of 32 cm Jaeger No. 1 represented in the original edition (1856) a visual acuity of 0.72 and 0.63 in the version from 1945 and the smallest print size of the Snellen reading test (1862) represented 0.55. Nieden No. 1 (1882) corresponded to a visual acuity of 0.59 and the smallest print size of the Birkhäuser cards (1911) 1.5. In the case of all reading cards except the original Birkhäuser cards, there was no logarithmic progression of the print sizes and the sizes of numbers were also not in accordance with the corresponding letter sizes. CONCLUSION: Print sizes of historical reading charts do not adhere to current standards and were usually not logarithmically scaled. These deficits and the lack of comparability between the historical reading charts may have caused reading cards to be currently underestimated as an accurate diagnostic tool. Nevertheless, the historical reading charts were the successful forerunners of developments for modern reading charts.

The history of the Greek Anti-Malaria League and the influence of the Italian School of Malariology.

In 1905, a group of eminent Greek physicians led by Professor of Hygiene and Microbiology Constantinos Savvas and the pediatrician Dr. Ioannis Kardamatis founded the Greek Anti-Malaria League. The League assumed a role that the State would not, and for the next 25 years organized the country's anti-malaria campaign. During its first steps, the Greek Anti-Malaria League adopted the principles of Professor Angelo Celli's Italian Anti-Malaria League. The League's accomplishments include a decrease in malarial prevalence, due to mass treatment with quinine, new legislation ensuring the provision of quinine, State monopoly and the collection of epidemiologic data. However, defeat in the Greek-Turkish War (1922) and the massive influx of one million Greek refugees that ensued, led to a change in malarial epidemiology. In 1928, following a visit to Italy, the Greek League adopted the organization and knowledge of the Italian Malaria Schools in Rome and in Nettuno, and this experience served as the basis of their proposal to the State for the development of the anti-malaria services infrastructure. The State adopted many of Professor Savvas' proposals and modified his plan according to Greek needs. The League's experience, accumulated during its 25 years of struggle against malaria, was its legacy to the campaigns that eventually accomplished the eradication of malaria from Greece after World War II.

Hans Driesch and the problems of "normal psychology". Rereading his Crisis in Psychology (1925).

In 1925, the German biologist and philosopher Hans Driesch published a booklet entitled The Crisis in Psychology. It was originally published in English and was based on lectures given at various universities in China, Japan and the USA. The "crisis" in psychology of that time, in Driesch's opinion, lies in the necessity to decide about "the road which psychology is to follow in the future". This necessity refers to five "critical points", namely (1) to develop the theory of psychic elements to a theory of meaning by phenomenological analysis, (2) the overcoming of association theory, (3) to acknowledge that the unconscious is a fact and a "normal" aspect of mental life, (4) to reject "psychomechanical parallelism" or any other epiphenomenalistic solution of the mind-body problem, and (5) the extension of psychical research to new facts as described by parapsychology, for instance. Driesch saw close parallels between the development of modern psychology and that of biology, namely in a theoretical shift from "sum-concepts" like association and mechanics, to "totality-concepts" like soul and entelechy. The German translation of 1926 was entitled Grundprobleme der Psychologie (Fundamental Problems of Psychology) while "the crisis in psychology" forms just the subtitle of this book. This underlines that Driesch's argumentation--in contrast to that of Buehler--dealt with ontological questions rather than with paradigms.

Maiden voyage.

The scientific debate which developed during the eighteenth century, proposed and diffused new theories on the generation not only within the scientific community. Microscopic investigation and various experimental campaigns fostered daring models attempting to unveil the natural phenomena from which life originates. Besides the famous scientific and philosophical works that marked the age, in the second part of the century two pamphlets appeared that well represent the importance of the querelle about embryological systems defining the concept of generation as a voyage within the human body. Lucina sine concubitu and Juno abortans, respectively published in England and in Germany between 1750 and 1760, narrate the odd and imaginary adventures of two doctors who are trying to interrupt and modify the embryos' journey towards the body of the mother.

Individuals at the center of biology: Rudolf Leuckart's Polymorphismus der Individuen and the ongoing narrative of parts and wholes. With an annotated translation.

Rudolf Leuckart's 1851 pamphlet Ueber den Polymorphismus der Individuen (On the polymorphism of individuals) stood at the heart of naturalists' discussions on biological individuals, parts and wholes in mid-nineteenth-century Britain and Europe. Our analysis, which accompanies the first translation of this pamphlet into English, situates Leuckart's contribution to these discussions in two ways. First, we present it as part of a complex conceptual knot involving not only individuality and the understanding of compound organisms, but also the alternation of generations, the division of labor in nature, and the possibility of finding general laws of the organic world. Leuckart's pamphlet is important as a novel attempt to give order to the strands of this knot. It also solved a set of key biological problems in a way that avoided some of the drawbacks of an earlier teleological tradition. Second, we situate the pamphlet within a longer trajectory of inquiry into part-whole relations in biology from the mid-eighteenth century to the present. We argue that biological individuality, along with the problem-complexes with which it engaged, was as central a problem to naturalists before 1859 as evolution, and that Leuckart's contributions to it left a long legacy that persisted well into the twentieth century. As biologists' interests in part-whole relations are once again on the upswing, the longue durée of this problem merits renewed consideration.

Selling eugenics: the case of Sweden.

This paper traces the early (1910s to 1920s) development of Swedish eugenics through a study of the social network that promoted it. The eugenics network consisted mainly of academics from a variety of disciplines, but with medicine and biology dominating; connections with German scientists who would later shape Nazi biopolitics were strong. The paper shows how the network used political lobbying (for example, using contacts with academically accomplished MPs) and various media strategies to gain scientific and political support for their cause, where a major goal was the creation of a eugenics institute (which opened in 1922). It also outlines the eugenic vision of the institute's first director, Herman Lundborg. In effect the network, and in particular Lundborg, promoted the view that politics should be guided by eugenics and by a genetically superior elite. The selling of eugenics in Sweden is an example of the co-production of science and social order.

Advertising cadavers in the republic of letters: anatomical publications in the early modern Netherlands.

This paper sketches how late seventeenth-century Dutch anatomists used printed publications to advertise their anatomical preparations, inventions and instructional technologies to an international clientele. It focuses on anatomists Frederik Ruysch (1638-1732) and Lodewijk de Bils (1624-69), inventors of two separate anatomical preparation methods for preserving cadavers and body parts in a lifelike state for decades or centuries. Ruysch's and de Bils's publications functioned as an 'advertisement' for their preparations. These printed volumes informed potential customers that anatomical preparations were aesthetically pleasing and scientifically important but did not divulge the trade secrets of the method of production. Thanks to this strategy of non-disclosure and advertisement, de Bils and Ruysch could create a well-working monopoly market of anatomical preparations. The 'advertising' rhetorics of anatomical publications highlight the potential dangers of equating the growth of print culture with the development of an open system of knowledge exchange.